Encyclopedia of Medical Immunology

2014 Edition
| Editors: Ian R. Mackay, Noel R. Rose, Dennis K. Ledford, Richard F. Lockey

Testing: High-Resolution Chest Computed Tomography Scan

Reference work entry
DOI: https://doi.org/10.1007/978-1-4614-9194-1_511


HRCT; Thin-section CT scan


High-resolution computed tomography (HRCT) chest scan is a powerful diagnostic tool for the evaluation of lung parenchyma. It can identify a wide array of findings that cannot be found with standard chest radiography or conventional helical CT scans. HRCT utilizes a high spatial frequency algorithm (bone) and thin 1 mm collimation, allowing for visualization of secondary pulmonary lobules and often interlobar fissures (Stark 2013).


The clinical indications for HRCT include the following: to aid with diagnosis in patients with nonspecific radiographic abnormalities, to confirm/exclude diffuse pulmonary disease in patients with functional abnormalities or normal/equivocal findings on other radiographic studies, and to potentially determine disease prognosis. In the setting of pulmonary fibrosis, disease reversibility is typically suggested by extensive ground-glass opacification; irreversible changes are more likely if...

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© Springer-Verlag Berlin Heidelberg 2014

Authors and Affiliations

  1. 1.Allergy & Asthma AssociatesHoustonUSA