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DNA Replication and Recombination in Plasmodium

  • Living reference work entry
  • First Online:
Encyclopedia of Malaria

Synonyms

DNA polymerase; Genome; Homologous recombination; Mitosis/meiosis; Rad proteins; Recombination machinery; Replication/duplication

Definition/Summary

DNA Replication: A fundamental biological process that is essential for multiplication and growth of living organisms. DNA replication is also the basis for biological inheritance of genetic traits. Some of the general eukaryotic DNA replication processes are conserved in the parasite; but replication process is distinct throughout the complex parasite life cycle due to different cell cycle. Genetic recombination is a process that cells engage in to create genetic variance. The process is also important for DNA repair in living cells and organisms. This review emphasizes the progress made so far in two of these important aspects of DNA metabolism: DNA replication and recombination in the malaria parasite.

DNA Replication

Introduction

The human malaria parasite Plasmodium falciparumalternates its life cycle between the human...

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Authors and Affiliations

  1. Department of Tropical Medicine, Tulane University School of Public Health and Tropical Medicine, 1440 Canal Street, SL-17, New Orleans, LA, 70112, USA

    Anusha M. Gopalakrishnan & Nirbhay Kumar

Authors
  1. Anusha M. Gopalakrishnan
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  2. Nirbhay Kumar
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Corresponding author

Correspondence to Nirbhay Kumar .

Editor information

Editors and Affiliations

  1. Heswall, United Kingdom

    Marcel Hommel

  2. Institut für Tropenmedizin, Universität Tübingen, Tübingen, Germany

    Peter G. Kremsner

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Gopalakrishnan, A.M., Kumar, N. (2013). DNA Replication and Recombination in Plasmodium . In: Hommel, M., Kremsner, P. (eds) Encyclopedia of Malaria. Springer, New York, NY. https://doi.org/10.1007/978-1-4614-8757-9_127-1

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  • DOI: https://doi.org/10.1007/978-1-4614-8757-9_127-1

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