The olivocerebellar pathway originates in the inferior olive in the brain stem, projects to the cerebellar cortex, and terminates as climbing fibers on the dendrites of the cerebellar cortical Purkinje cells.
Cerebellar Function and Information Processing
The cerebellum is involved in a wide range of processes, including cognitive functions (Thach 1996; Schmahmann 1997, 2010), but is best known for its pivotal role in the control of movement. This role is usually described as regulatory, as the cerebellum is in principle not essential for initiation or execution of movements. Rather, cerebellar deficits result in a lack of coordination (Babinski 1899, 1906; Holmes 1917, 1939; Chambers and Sprague 1955; Dow and Moruzzi 1958; Ito 1984).
The regions of the cerebellum that are related to motor control receive a wide variety of sensory inputs and generate motor-related outputs according to internal rules of computation. These rules are determined by the...
KeywordsPurkinje Cell Cerebellar Cortex Inferior Olive Climbing Fiber Muscle Synergy
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