Local Field Potentials (LFP)
The local field potential (LFP) is the electric potential in the extracellular medium around neurons. The LFP is signal available in many recording configurations, ranging from single-electrode recordings to multielectrode arrays. The LFP has specific spatial and temporal properties and also depends on the brain state. Different classes of models are used to model the LFP.
The local field potential (LFP) is the electric potential in the extracellular space around neurons and can be recorded using different types of microelectrodes (metal, silicon, or glass micropipettes). These characteristics differ from the electroencephalogram (EEG), which is recorded at the surface of the scalp with macro-electrodes. It was shown that the LFP samples relatively localized populations of neurons, as these signals can be very different for electrodes separated by 1 mm (Destexhe et al. 1999) or even by a few hundred microns (Katzner et al. 2009). In...
KeywordsSlow Wave Ionic Diffusion Extracellular Medium Local Field Potential Brain State
- Destexhe A, Bédard C (2013) Local field potential. Scholarpedia, 8:10713. http://www.scholarpedia.org/article/Local_field_potential
- Niedermeyer E, Lopes da Silva F (eds) (1998) Electroencephalography, 4th edn. Williams and Wilkins, BaltimoreGoogle Scholar
- Nunez PL, Srinivasan R (2005) Electric fields of the brain, 2nd edn. Oxford university press, Oxford, UKGoogle Scholar
- Protopapas AD, Vanier M, Bower J (1998) Simulating large-scale networks of neurons. In: Koch C, Segev I (eds) Methods in neuronal modeling, 2nd edn. MIT Press, Cambridge, MA, pp 461–498Google Scholar
- Steriade M (2003) Neuronal substrates of sleep and epilepsy. Cambridge University Press, Cambridge, UKGoogle Scholar
- Wagner T, Eden U, Rushmore J, Russo CJ, Dipietro L, Fregni F, Simon S, Rotman S, Pitskel NB, Ramos-Estebanez C, Pascual-Leone A, Grodzinsky AJ, Zahn M, Valero-Cabre A (2014) Impact of brain tissue filtering on neurostimulation fields: a modeling study. NeuroImage 85:1048–1057PubMedCrossRefGoogle Scholar