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SenseLab: Integration of Multidisciplinary Neuroscience Data

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Encyclopedia of Computational Neuroscience

Definition

The SenseLab project involves novel informatics approaches to constructing databases and Web-enabled applications for collecting, modeling, analyzing, and sharing neuroscience information. The emphasis of SenseLab (http://www.senselab.org) is on building experimental data into integrated, multidisciplinary models of neurons and neural systems in order to gain insight into the neural basis of behavior. SenseLab is also part of the Neuroscience Information Framework (NIF) project and the International Neuroinformatics Coordinating Facility (INCF).

Detailed Description

SenseLab was founded in 1993 as part of the original Human Brain Project sponsored by the National Institutes of Health, National Science Foundation, and several other government funding agencies in the United States, which began the development of neuroinformatics tools in support of neuroscience research. Using the olfactory system as a model, SenseLab has built a suite of nine databases (see Fig. 1) to...

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References

  • Buck L, Axel R (1991) A novel multigene family may encode odorant receptors – a molecular-basis for odor recognition. Cell 65:175–187

    Article  CAS  PubMed  Google Scholar 

  • Hines ML, Carnevale NT (2014) NEURON Simulation Environment. In: Kotaleski JH, Crook S, (eds) Encyclopedia of computational neuroscience, Springer

    Google Scholar 

  • Migliore M, Cavarretta F, Hines ML, Shepherd GM (2013) Functional neurology of a brain system: a 3D olfactory bulb model to process natural odorants. Funct Neurol 2013 28(3):241–243

    PubMed Central  PubMed  Google Scholar 

  • Pechura CM, Martin JB (1991) Mapping the brain and its functions: integrating enabling technologies into neuroscience research. National Academy Press, Washington, DC

    Google Scholar 

  • Rall W, Shepherd GM (1968) Theoretical reconstruction of field potentials and dendrodendritic synaptic interactions in olfactory bulb. J neurophysiol 31:884–915

    CAS  PubMed  Google Scholar 

  • Shepherd GM (2004) The synaptic organization of the brain, 5th edn. Oxford University Press, Oxford

    Book  Google Scholar 

  • Shepherd GM, Grillner S (2010) Handbook of brain microcircuits. Oxford University Press, New York

    Book  Google Scholar 

  • Yu Y, McTavish TS, Hines ML, Shepherd GM, Valenti C, Migliore M (2013) Sparse distributed representation of odors in a large-scale olfactory bulb circuit. PLoS Comput Biol 9:e1003014

    Article  CAS  PubMed Central  PubMed  Google Scholar 

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Acknowledgments

We gratefully acknowledge funding from NIH grant DC009977.

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Correspondence to Gordon M. Shepherd .

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Shepherd, G.M. et al. (2013). SenseLab: Integration of Multidisciplinary Neuroscience Data. In: Jaeger, D., Jung, R. (eds) Encyclopedia of Computational Neuroscience. Springer, New York, NY. https://doi.org/10.1007/978-1-4614-7320-6_497-1

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  • DOI: https://doi.org/10.1007/978-1-4614-7320-6_497-1

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  • Online ISBN: 978-1-4614-7320-6

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