Definition
Eye-blink conditioning is both a procedure and a type of learning. The delay procedure includes the repeated presentation of a conditioned stimulus (CS) that does not elicit eyelid closure before training followed shortly (150–2000 ms) by an unconditioned stimulus (US) that elicits an eyelid closure unconditioned response (UR) before training. After repeated paired presentations of the CS and US, the organism will develop an eyelid closure conditioned response (CR) which precedes the onset of the US (Fig. 1). Unpaired presentations of the CS and US do not result in the development of a CR. Eye-blink conditioning therefore establishes associative learning based upon the predictive relationship between the CS and US – the CS predicts that the US is coming. It also establishes learned timing such that maximum eyelid closure for the CR is timed to the onset of the US in well-trained...
This is a preview of subscription content, log in via an institution to check access.
References
Albus JS (1971) A theory of cerebellar function. Math Biosci 10(1–2):25–61
Attwell PJ, Cooke SF, Yeo CH (2002) Cerebellar function in consolidation of a motor memory. Neuron 34(6):1011
Freeman JH, Steinmetz AB (2011) Neural circuitry and plasticity mechanisms underlying delay eyeblink conditioning. Learning & memory (Cold Spring Harbor, NY) 18(10):666. https://doi.org/10.1101/lm.2023011
Halverson HE, Lee I, Freeman JH (2010) Associative plasticity in the medial auditory thalamus and cerebellar interpositus nucleus during eyeblink conditioning. J Neurosci Off J Soc Neurosci 30(26):8787. https://doi.org/10.1523/jneurosci.0208-10.2010
Jirenhed DA, Bengtsson F, Hesslow G (2007) Acquisition, extinction, and reacquisition of a cerebellar cortical memory trace. J Neurosci Off J Soc Neurosci 27(10):2493. https://doi.org/10.1523/jneurosci.4202-06.2007
Krupa DJ, Thompson JK, Thompson RF (1993) Localization of a memory trace in the mammalian brain. Science (New York) 260(5110):989
Li WK, Hausknecht MJ, Stone P, Mauk MD (2013) Using a million cell simulation of the cerebellum: network scaling and task generality. Neural Netw Offic J Int Neural Netw Soc 47:95. https://doi.org/10.1016/j.neunet.2012.11.005
Marr D (1969) A theory of cerebellar cortex. J Physiol 202(2):437–470
McCormick DA, Thompson RF (1984) Cerebellum: essential involvement in the classically conditioned eyelid response. Science (New York) 223(4633):296
Author information
Authors and Affiliations
Corresponding author
Editor information
Editors and Affiliations
Section Editor information
Rights and permissions
Copyright information
© 2019 Springer Science+Business Media, LLC, part of Springer Nature
About this entry
Cite this entry
Freeman, J.H. (2019). Eye-Blink Conditioning. In: Jaeger, D., Jung, R. (eds) Encyclopedia of Computational Neuroscience. Springer, New York, NY. https://doi.org/10.1007/978-1-4614-7320-6_474-1
Download citation
DOI: https://doi.org/10.1007/978-1-4614-7320-6_474-1
Received:
Accepted:
Published:
Publisher Name: Springer, New York, NY
Print ISBN: 978-1-4614-7320-6
Online ISBN: 978-1-4614-7320-6
eBook Packages: Springer Reference Biomedicine and Life SciencesReference Module Biomedical and Life Sciences