Encyclopedia of Computational Neuroscience

Living Edition
| Editors: Dieter Jaeger, Ranu Jung

Retinal Waves, Models of

  • Matthias H. HennigEmail author
Living reference work entry
DOI: https://doi.org/10.1007/978-1-4614-7320-6_399-1

Definition

The developing retina displays spontaneous activity characterized by correlated, propagating activity patterns (Wong 1999; Blankenship and Feller 2010). Retinal waves are hypothesized to provide cues for the development of retinal receptive fields and projections from the retina to higher visual brain areas (Sernagor et al. 2001; Torborg and Feller 2005). Several computational models have been developed to simulate retinal waves, which have helped to shed light on the mechanisms involved in their generation (Godfrey and Eglen 2009). Two different approaches have been used in these models; they simulate networks either as cellular automata or using biophysical neurons models. These models also provide tools for generating synthetic activity to investigate the role of retinal waves in models of visual system development.

Detailed Description

Since their discovery in 1988 (Galli and Maffei 1988; Wong et al. 1993), there has been intensive research into the mechanisms...

Keywords

Ganglion Cell Cellular Automaton Amacrine Cell Patch Clamp Recording Refractory State 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.
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Copyright information

© Springer Science+Business Media New York 2014

Authors and Affiliations

  1. 1.Institute for Adaptive and Neural Computation, School of InformaticsUniversity of EdinburghEdinburghUK