Models of Fly Lobula Plate Tangential Cells (LPTCs)
A network of around 60 highly interconnected interneurons, the lobula plate tangential cells (LPTCs), is at the core of optic flow calculations in the fly visual system. Exquisite data is available for these cells on their anatomy and electrophysiology in vivo, including the characterization of responses to visual stimulation. Consequently, it has been possible to derive models that reproduce the morphology and the detailed electrophysiology of the cells within the network and to associate the features of the network to optic flow computations that it performs. The LPTC network therefore is a prime example of a neural circuit where sophisticated computations, connectivity schemes, and anatomy are understood in a unifying manner.
Circuit Overview of the Lobula Plate
The lobula plate in the fly is a neural center for course control during flight (Borst and Haag 2002). It encodes visual motion information in a retinotopic manner: Neighborhood relationships...
I would like to thank Alexander Borst for the helpful discussions and for reading this manuscript.
- Egelhaaf M (1985b) On the neuronal basis of figure-ground discrimination by relative motion in the visual system of the fly. II. Figure-detection cells, a new class of visual interneurones. Biol Cybern 52:195–209Google Scholar
- Hassenstein B, Reichardt W (1956) Systemtheoretische analyze der zeit-, reihenfolgen- und vorzeichenauswertung bei der bewegungsperzeption des rüsselkäfers chlorophanus. Zeitschrift fuer Naturforsch 11b:513–524Google Scholar
- Reichardt W (1961) Autocorrelation, a principle for the evaluation of sensory information by the central nervous system. In: Rosenblith WA (ed) Sensory communication. MIT Press/Wiley, New York, pp 377–390Google Scholar
- Rieke F, Warland DK, de Ruyter van Steveninck RR, Bialek W (1999) Spikes – exploring the neural code. MIT Press, Cambridge, MAGoogle Scholar