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Phase Resetting, Measurement of Infinitessimal

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Encyclopedia of Computational Neuroscience

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Definition

The infinitesimal phase response curve (iPRC) is a measure of an oscillator, which specifies how the phase of that oscillator shifts, as a function of the phase of a perturbation as the width and height of the pulse go to zero, approximating a continuous time delta function (see “Weak Coupling Theory”). In neurons, the iPRC measures the spike time shift in response to the injection of a small current (or less often a conductance) pulse at a given time. The iPRC should scale linearly with pulse area.

Detailed Description

The iPRC of neurons is of interest for several reasons. First, by using the iPRC, a prediction can be made about the synchronizing properties of synaptically coupled neurons. Given small conduction delays and weak coupling between neurons, nonnegative PRCs (type I PRCs or monophasic PRCs; see “Phase Response Curve, Measurement and Shape of General”) typically lead to synchronization between neurons only if they are coupled via inhibitory connections. In...

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Further Reading

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Author information

Authors and Affiliations

  1. The MARCS Institute, University of Western Sydney, Penrith, Australia

    Dr. Klaus Stiefel

Authors
  1. Dr. Klaus Stiefel
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Correspondence to Klaus Stiefel .

Editor information

Editors and Affiliations

  1. Atlanta, Georgia, USA

    Dieter Jaeger

  2. Department of Biomedical Engineering, Florida International University, Miami, Florida, USA

    Ranu Jung

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Stiefel, K. (2014). Phase Resetting, Measurement of Infinitessimal. In: Jaeger, D., Jung, R. (eds) Encyclopedia of Computational Neuroscience. Springer, New York, NY. https://doi.org/10.1007/978-1-4614-7320-6_267-1

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  • DOI: https://doi.org/10.1007/978-1-4614-7320-6_267-1

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  • Publisher Name: Springer, New York, NY

  • Online ISBN: 978-1-4614-7320-6

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