Reduced Morphology Models
Reduced morphology models are simplified computational models obtained by collapsing the dendritic tree of a detailed neuron model, in such a way to preserve as much as possible the original membrane dynamics.
Morphologically detailed neuron models are based on 3D anatomical cell reconstructions and describe how the spatial dendritic structure of a neuron together with the kinetic properties and distributions of ion channels and synaptic inputs contributes to the dynamics and functionality of a neuron. These compartmental neuron models are usually composed of hundreds of dendritic branches (Fig. 1) with nonlinear membrane properties.
KeywordsPurkinje Cell Proper Orthogonal Decomposition Synaptic Input Dendritic Tree Axial Resistance
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