Emergence of Orientation Selectivity in the Cerebral Cortex, Modeling
- 125 Downloads
Orientation tuning is a characteristic response property of neurons in primary visual cortex. Models of orientation tuning describe the transformation of response selectivity from lateral geniculate relay cells, which are not orientation selective, to neurons in layer 4 of the primary visual cortex. These models aim to constrain and identify the neural circuitry underlying this canonical transformation in the representation of the visual world.
The overarching goal of systems neuroscience is to explain how the sensory inputs we receive are integrated to generate appropriate behaviors. One method of achieving this goal is to study the mechanisms underlying a single computation and build models which may be applied more generally. Computations performed by the cerebral cortex are amenable to this approach due to the relative uniformity of cortical circuitry. Not only does mammalian cerebral cortex contain a common set of neuron cell types with...
- Bishop PO, Coombs JS, Henry GH (1973) Receptive fields of simple cells in the cat striate cortex. J Physiol (Lond) 231:31–60Google Scholar
- Gilbert C (1977) Laminar differences in receptive field properties of cells in cat primary visual cortex. J Physiol (Lond) 268:391–421Google Scholar
- Hubel D, Wiesel T (1962) Receptive fields, binocular interaction and functional architecture in the cat’s visual cortex. J Physiol (Lond) 160:106–154Google Scholar
- Jones JP and Palmer LA (1987) An evaluation of the two-dimensional Gabor filter model of simple cell receptive fields in cat striate cortex. J Neurophysiol 50(6):1233–1258Google Scholar
- Martin K (1988) From single cells to simple circuits in the cerebral cortex. J Exp Physiol 73:637–702Google Scholar
- Martinez LM, Wang Q, Reid RC, Pillai C, Alonso JM, Sommer FT, Hirsch JA (2006) Receptive field structure varies with layer in the primary visual cortex. Nat Neurosci 8:372–379Google Scholar
- Sadogopan S, Ferster D (2012) Feedforward origins of response variability underlying contrast invariant orientation tuning in cat visual cortex. Neuron 74:911–923Google Scholar