Encyclopedia of Computational Neuroscience

2015 Edition
| Editors: Dieter Jaeger, Ranu Jung

Emergence of Orientation Selectivity in the Cerebral Cortex, Modeling

  • Benjamin Scholl
  • Nicholas J. PriebeEmail author
Reference work entry
DOI: https://doi.org/10.1007/978-1-4614-6675-8_576


Orientation tuning is a characteristic response property of neurons in primary visual cortex. Models of orientation tuning describe the transformation of response selectivity from lateral geniculate relay cells, which are not orientation selective, to neurons in layer 4 of the primary visual cortex. These models aim to constrain and identify the neural circuitry underlying this canonical transformation in the representation of the visual world.

Detailed Description


The overarching goal of systems neuroscience is to explain how the sensory inputs we receive are integrated to generate appropriate behaviors. One method of achieving this goal is to study the mechanisms underlying a single computation and build models which may be applied more generally. Computations performed by the cerebral cortex are amenable to this approach due to the relative uniformity of cortical circuitry. Not only does mammalian cerebral cortex contain a common set of neuron cell types with...

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Authors and Affiliations

  1. 1.Section of NeurobiologyThe University of Texas at AustinAustinUSA