Definition
A biophysical model of spike-timing-dependent plasticity (STDP) is one which converts time intervals, in a given firing pattern of synaptically coupled pre- and postsynaptic neurons, to modifications of the connecting synapse. This class of STDP model is defined by their mathematical representation of specific biophysical quantities, which have been shown to play a role in the intracellular mechanisms underlying synaptic plasticity.
Detailed Description
Within the STDP framework, models of synaptic plasticity are dependent on the precise relative timing of pre- and postsynaptic spikes and, broadly speaking, utilize one, or a combination, of two modelling approaches. The first group of STDP models use phenomenological modelling to empirically describe the relationship between the model inputs (pre- and postsynaptic spike times) and the model output (synaptic weight modification). There is usually little or no attempt to represent the intracellular machinery governing synaptic...
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Griffith, T., Mellor, J., Tsaneva-Atanasova, K. (2015). Spike-Timing Dependent Plasticity (STDP), Biophysical Models. In: Jaeger, D., Jung, R. (eds) Encyclopedia of Computational Neuroscience. Springer, New York, NY. https://doi.org/10.1007/978-1-4614-6675-8_359
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DOI: https://doi.org/10.1007/978-1-4614-6675-8_359
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