Encyclopedia of Computational Neuroscience

2015 Edition
| Editors: Dieter Jaeger, Ranu Jung

Insect Olfaction: a Model System for Neural Circuit Modeling

  • Nitin Gupta
  • Mark Stopfer
Reference work entry
DOI: https://doi.org/10.1007/978-1-4614-6675-8_338

Definition

Insect olfactory system denotes the network of cells – including the sensory neurons located on the antennae and the interneurons located in several areas of the brain such as the antennal lobe, the mushroom body, and the lateral horn – that work together to enable the sense of smell in an insect. Here we describe this circuit and consider why it makes a good model system for computational modeling of neural circuits.

Detailed Description

Olfaction presents some difficult problems. Unlike the visual or the auditory system, whose stimuli – light or sound – can be described along the dimensions of frequency and intensity, the olfactory system works with volatile chemicals, which come in numerous shapes and sizes, defying easy description in one or a few dimensions. But, like visual and auditory stimuli, olfactory stimuli may also vary in their intensity, timing, or spatial distribution. It remains a puzzle how the brain makes sense of this multidimensional input (Laurent 2002)....

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References

  1. Bazhenov M, Stopfer M, Sejnowski TJ, Laurent G (2005) Fast odor learning improves reliability of odor responses in the locust antennal lobe. Neuron 46:483–492PubMedCentralPubMedGoogle Scholar
  2. Brown SL, Joseph J, Stopfer M (2005) Encoding a temporally structured stimulus with a temporally structured neural representation. Nat Neurosci 8:1568–1576PubMedGoogle Scholar
  3. Das S, Sadanandappa MK, Dervan A, Larkin A, Lee JA, Sudhakaran IP, Priya R, Heidari R, Holohan EE, Pimentel A, Gandhi A, Ito K, Sanyal S, Wang JW, Rodrigues V, Ramaswami M (2011) Plasticity of local GABAergic interneurons drives olfactory habituation. Proc Natl Acad Sci U S A 108:E646–E654PubMedCentralPubMedGoogle Scholar
  4. Gupta N, Stopfer M (2011) Insect olfactory coding and memory at multiple timescales. Curr Opin Neurobiol 21:768–773PubMedCentralPubMedGoogle Scholar
  5. Gupta N, Stopfer M (2012) Functional analysis of a higher olfactory center, the lateral horn. J Neurosci 32:8138–8148PubMedCentralPubMedGoogle Scholar
  6. Hallem EA, Carlson JR (2006) Coding of odors by a receptor repertoire. Cell 125:143–160PubMedGoogle Scholar
  7. Hansson BS (1999) Insect olfaction. Springer, BerlinGoogle Scholar
  8. Hildebrand JG, Shepherd GM (1997) Mechanisms of olfactory discrimination: converging evidence for common principles across phyla. Annu Rev Neurosci 20:595–631PubMedGoogle Scholar
  9. Kay LM, Stopfer M (2006) Information processing in the olfactory systems of insects and vertebrates. Semin Cell Dev Biol 17:433–442PubMedGoogle Scholar
  10. Kenyon FC (1896) The brain of the bee – a preliminary contribution to the morphology of the nervous system of the Arthropoda. J Comp Neurol 6:134–210Google Scholar
  11. Laurent G (2002) Olfactory network dynamics and the coding of multidimensional signals. Nat Rev Neurosci 3:884–895PubMedGoogle Scholar
  12. Papadopoulou M, Cassenaer S, Nowotny T, Laurent G (2011) Normalization for sparse encoding of odors by a wide-field interneuron. Science 332:721–725PubMedCentralPubMedGoogle Scholar
  13. Perez-Orive J, Mazor O, Turner GC, Cassenaer S, Wilson RI, Laurent G (2002) Oscillations and sparsening of odor representations in the mushroom body. Science 297:359–365PubMedGoogle Scholar
  14. Raman B, Joseph J, Tang J, Stopfer M (2010) Temporally diverse firing patterns in olfactory receptor neurons underlie spatiotemporal neural codes for odors. J Neurosci 30:1994–2006PubMedCentralPubMedGoogle Scholar
  15. Stopfer M, Laurent G (1999) Short-term memory in olfactory network dynamics. Nature 402:664–668PubMedGoogle Scholar
  16. Stopfer M, Jayaraman V, Laurent G (2003) Intensity versus identity coding in an olfactory system. Neuron 39:991–1004PubMedGoogle Scholar
  17. Su C-Y, Menuz K, Reisert J, Carlson JR (2012) Non-synaptic inhibition between grouped neurons in an olfactory circuit. Nature 492:66–71PubMedCentralPubMedGoogle Scholar
  18. Sudhakaran IP, Holohan EE, Osman S, Rodrigues V, Vijayraghavan K, Ramaswami M (2012) Plasticity of recurrent inhibition in the Drosophila antennal lobe. J Neurosci 32:7225–7231PubMedGoogle Scholar
  19. Vermeulen A, Rospars JP (2001) Membrane potential and its electrode-recorded counterpart in an electrical model of an olfactory sensillum. Eur Biophys J 29:587–596PubMedGoogle Scholar
  20. Vermeulen A, Rospars JP (2004) Why are insect olfactory receptor neurons grouped into sensilla? The teachings of a model investigating the effects of the electrical interaction between neurons on the transepithelial potential and the neuronal transmembrane potential. Eur Biophys J 33:633–643PubMedGoogle Scholar
  21. Wehr M, Laurent G (1999) Relationship between afferent and central temporal patterns in the locust olfactory system. J Neurosci 19:381–390PubMedGoogle Scholar

Copyright information

© Springer Science+Business Media New York 2015

Authors and Affiliations

  • Nitin Gupta
    • 1
  • Mark Stopfer
    • 1
  1. 1.National Institutes of HealthNICHDBethesdaUSA