Synonyms
Definition (and Description)
Antigens are antibody generators, any foreign material which is recognized by the body as foreign and causes the production of antibodies.
Antigens can be bacteria, viruses, toxins, or foreign nonself materials. A molecular part of a microorganism or foreign material that is recognized by immune cells is the part which is called antigen. Certain cells of the immune system (B and T lymphocytes) recognize antigen by their specific receptors. B cells (matured in the bone marrow) are the immune cells that recognize antigen via their surface receptors or antibody. T cells (matured in the thymus) recognize antigen via their T-cell receptor, but only after antigens have been processed into smaller peptides by antigen-presenting immune cells. Vaccines work by presenting a dead or altered form of an antigen to the immune system in order to provoke a response.
Cross-References
References and Further Readings
Goldsby, R. A., Kindt, T. J., Osborne, B. A., & Kuby, J. (2003). Immunology (5th ed.). New York: W.H. Freeman.
Author information
Authors and Affiliations
Corresponding author
Editor information
Editors and Affiliations
Rights and permissions
Copyright information
© 2018 Springer Science+Business Media, LLC, part of Springer Nature
About this entry
Cite this entry
Whittaker, A.C. (2018). Antigens. In: Gellman, M. (eds) Encyclopedia of Behavioral Medicine. Springer, New York, NY. https://doi.org/10.1007/978-1-4614-6439-6_440-3
Download citation
DOI: https://doi.org/10.1007/978-1-4614-6439-6_440-3
Received:
Accepted:
Published:
Publisher Name: Springer, New York, NY
Print ISBN: 978-1-4614-6439-6
Online ISBN: 978-1-4614-6439-6
eBook Packages: Springer Reference MedicineReference Module Medicine