Hostility, Psychophysiological Responses
Hostility has distinct cognitive components, affective or emotional components, and behavioral features. This multidimensional construct most commonly is defined by a mistrustful and suspicious attitude, cynical perceptions of others and their motives, and a negative interactional style characterized by anger, resentment, contempt, antagonism, and suspiciousness. Behavioral expressions of hostility typically include verbally and/or physically aggressive actions. The physiological consequences of hostility and its components contribute to over-activation of neurochemical and biological pathways, consistent with the stress response system, which may contribute to atherogenesis and alterations in glucose metabolism and other bodily systems and which are harmful to cardiovascular health.
A wealth of research has investigated physiologic responses related to hostility (Everson-Rose...
References and Further Reading
- Cervilla, J. A., Molina, E., Rivera, M., Torres-González, F., Bellón, J. A., Moreno, B., et al. (2007). The risk for depression conferred by stressful life events is modified by variation at the serotonin transporter 5HTTLPR genotype: Evidence from the Spanish PREDICT-Gene cohort. Molecular Psychiatry, 12, 748–755.CrossRefGoogle Scholar
- Manuck, S. B., Flory, J. D., Ferrel, R. E., Mann, J., & Muldoon, M. F. (2000). A regulatory polymorphism of the monoamine oxidase-A gene may be associated with variability in aggression, impulsivity, and central nervous system serotonergic responsivity. Journal of Psychiatric Research, 95, 9–23.CrossRefGoogle Scholar