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BRCA1 and BRCA2

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  • First Online:
Encyclopedia of Signaling Molecules

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Synonyms

BRCA1: Brca1; BRCA1/BRCA2-containing complex, subunit 1; BRCAI; BRCC1; Breast and ovarian cancer susceptibility protein 1; Breast cancer 1; Breast cancer 1, early onset; Breast cancer type 1 susceptibility protein; Breast cancer type 1 susceptibility protein homolog; IRIS; PSCP; RING finger protein 53; RNF53

BRCA2: BRCA1/BRCA2-containing complex, subunit 2; Brca2; BRCC2; Breast and ovarian cancer susceptibility gene, early onset; Breast cancer 2; Breast cancer 2 tumor suppressor; Breast cancer 2, early onset; Breast cancer susceptibility protein BRCA2; Breast cancer type 2 susceptibility protein homolog; FACD; FAD; FAD1; FANCB; FANCD; Fancd1; Fanconi anemia group D1 protein; Fanconi anemia group D1 protein homolog; RAB163

Historical Background

Most breast and ovarian cancers (BOC) are sporadic, meaning they occur by chance with no known cause. A diagnosis of hereditary breast and ovarian cancer syndrome (HBOC) has been considered when multiple cases of breast and/or ovarian...

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References

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Authors and Affiliations

  1. Instituto de Investigaciones Bioquímicas (INBIOMED), Facultad de Medicina, Universidad de Buenos Aires-CONICET, Buenos Aires, Argentina

    Angela R. Solano, Pablo G. Mele & Ernesto J. Podesta

  2. Genotipificación y Cáncer Hereditario, Centro de Educación Médica e Investigaciones Clínicas “Norberto Quirno” (CEMIC), Buenos Aires, Argentina

    Angela R. Solano & Florrcencia C. Cardoso

Authors
  1. Angela R. Solano
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  2. Florrcencia C. Cardoso
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  3. Pablo G. Mele
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  4. Ernesto J. Podesta
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Corresponding author

Correspondence to Ernesto J. Podesta .

Editor information

Editors and Affiliations

  1. Dept. Biological Science, Department of Molecular Science and Tech College of Natural Science, Suwon, Korea (Republic of)

    Sangdun Choi

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Solano, A.R., Cardoso, F.C., Mele, P.G., Podesta, E.J. (2016). BRCA1 and BRCA2. In: Choi, S. (eds) Encyclopedia of Signaling Molecules. Springer, New York, NY. https://doi.org/10.1007/978-1-4614-6438-9_101898-1

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  • DOI: https://doi.org/10.1007/978-1-4614-6438-9_101898-1

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  • Print ISBN: 978-1-4614-6438-9

  • Online ISBN: 978-1-4614-6438-9

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