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NDFIP1 and NDFIP2

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  • First Online:
Encyclopedia of Signaling Molecules

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Synonyms

Ndfip1:

Bypass Sod1p Defects (Bsd2p) (Saccharomyces cerevisiae); Nedd4 family-interacting protein 1 (Ndfip1); Nedd4 family-interacting protein (Ndfip), dNdfip, DmeI, CG32177 (Drosophila Ndfip1); NEDD4 WW domain-binding protein 5 (human); Nedd4 WW domain-binding protein 5 (N4WBP5)

Ndfip2:

KIAA1165; Nedd4 family-interacting protein 2 (Ndfip2); NEDD4 WW domain-binding protein 5A (N4WBP5A)

Historical Background

Nedd4 family-interacting protein 1 (Ndfip1) was first identified in a far-western screen searching for proteins that interact with the WW domains of the Nedd4 ubiquitin ligase (Jolliffe et al. 2000). It was initially named Nedd4 WW domain-binding protein 5 (N4WBP5). Following this discovery, a closely related mammalian protein was identified (named N4WBP5A, now called Ndfip2) and further characterized as belonging to a small group of evolutionarily conserved proteins (Harvey et al. 2002), with a single homologue in yeast [Bsd2p (Hettema et al., 2004)] and Drosophila...

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References

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Authors and Affiliations

  1. Centre for Cancer Biology, University of South Australia, 5001, Adelaide, SA, Australia

    Natalie Foot & Sharad Kumar

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  1. Natalie Foot
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  2. Sharad Kumar
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Corresponding author

Correspondence to Sharad Kumar .

Editor information

Editors and Affiliations

  1. Dept. Biological Science, Department of Molecular Science and Tech College of Natural Science, Suwon, Korea (Republic of)

    Sangdun Choi

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Foot, N., Kumar, S. (2016). NDFIP1 and NDFIP2. In: Choi, S. (eds) Encyclopedia of Signaling Molecules. Springer, New York, NY. https://doi.org/10.1007/978-1-4614-6438-9_101705-1

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  • DOI: https://doi.org/10.1007/978-1-4614-6438-9_101705-1

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  • Online ISBN: 978-1-4614-6438-9

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