Encyclopedia of Autism Spectrum Disorders

Living Edition
| Editors: Fred R. Volkmar

Periventricular Leukomalacia

  • Jennifer M. KwonEmail author
Living reference work entry
DOI: https://doi.org/10.1007/978-1-4614-6435-8_684-3




Periventricular leukomalacia (PVL) is the most common ischemic brain injury in premature infants and occurs in the white matter adjacent to the lateral ventricles, just distal to the regions supplied by the deep branches of the middle cerebral arteries. PVL is diagnosed by the typical findings of echodensities on cerebral ultrasound or signal abnormalities of MRI. PVL is an important finding because of the high association with later development of nonprogressive developmental impairments such as cerebral palsy.

See Also

References and Reading

  1. Volpe, J. J. (2008). Neurology of the newborn (5th ed.). Philadelphia: Saunders Elsevier. Chapter 8.Google Scholar

Copyright information

© Springer Science+Business Media, LLC, part of Springer Nature 2018

Authors and Affiliations

  1. 1.Department of Neurology & Pediatrics (SMD)University of Rochester, School of Medicine and DentistryRochesterUSA