Cleft Lip and/or Cleft Palate
Cleft lip or palate (CL/CP) is the most common craniofacial malformation with an estimated incidence from approximately 1 in 700 to 1 in 1,000 live births among Caucasians (Carinci et al. 2000). CL/CP may occur as an isolated finding or may be found in association with other congenital malformations.
KeywordsInterferon Methotrexate Folic Acid Smoke Stein
- Chen, H. (1988). Medical genetics handbook (pp. 320–321). St Louis: Warren H Green.Google Scholar
- Habib, Z. (1978a). Factors determining occurrence of cleft lip and cleft palate. Surgery, Gynecology & Obstetrics, 146, 105–110.Google Scholar
- Jackson, A., Bromley, R., Morrow, J., et al. (2015). In utero exposure to valproate increases the risk of isolated cleft palate. Archives of Disease in Childhood. Fetal Neonatal Edition, F1–F5. [Epub ahead of print].Google Scholar
- van der Woude, A. (1954). Fistula labii inferioris congenita and its association with cleft lip and palate. American Journal of Human Genetics, 6, 244–256.Google Scholar