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Cerebral Palsy

Living reference work entry

Abstract

Cerebral palsy (CP) is currently considered as a clinically defined symptom complex applied to individuals with a static, nonprogressive motor impairment of early onset that is cerebral in origin. It describes a group of motor impairment syndromes secondary to genetic and acquired disorders of the developing brain. Therefore, it is not a single entity with respect to pathogenesis but rather an etiologically heterogeneous entity with multiple possible causes that result in an aberration or injury to the maturing central nervous system. The motor disorders of cerebral palsy are often accompanied by disturbances of sensation, cognition, communication, perception, and/or behavior and/or by a seizure disorder. The prevalence is estimated between 1.5 and 2.5 per 1,000 live births (Ferriero 1999).

Keywords

Cerebral Palsy Rectus Femoris Rett Syndrome Angelman Syndrome Hereditary Spastic Paraplegia 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

References

  1. Agarwal, A., > Verma, I. (2012). Cerebral palsy in children: An overview. Journal of Clinical Orthopaedics and Trauma, 3, 77–81.CrossRefPubMedPubMedCentralGoogle Scholar
  2. Ashwal, S., Russman, B. S., Blasco, P. A., et al. (2004). Practice parameter: Diagnostic assessment of the child with cerebral palsy. Report of the Quality Standards Subcommittee of the American Academy of Neurology and the Practice Committee of the Child Neurology Society. Neurology, 62, 851–863.CrossRefPubMedGoogle Scholar
  3. Balakrishnan, B., Nance, E., Johnston, M. V., et al. (2013). Nanomedicine in cerebral palsy. International Journal of Nanomedicine, 8, 4183–4195.PubMedPubMedCentralGoogle Scholar
  4. Bax, M., Goldstein, M., Rosenbaum, P., et al. (2005). Proposed definition and classification of cerebral palsy, April 2005. Developmental Medicine and Child Neurology, 47, 571–576.CrossRefPubMedGoogle Scholar
  5. Berker, A. N., > Yalçin, M. S. (2008). Cerebral palsy: Orthopedic aspects and rehabilitation. Pediatric Clinics of North America, 55, 1209–1225.CrossRefPubMedGoogle Scholar
  6. Blair, E., Watson, L., Badawi, N., et al. (2001). Life expectancy among people with cerebral palsy in Western Australia. Developmental Medicine and Child Neurology, 43, 508–515.CrossRefPubMedGoogle Scholar
  7. Chinnery, D. F. (2014). Mitochondrial disorders overview. GeneReviews. Updated August 14, 2014. Available at UTP: http://www.ncbi.nlm.nih.gov/books/BNBK1224/.
  8. Dodge, N. N. (2008). Cerebral palsy: Medical aspects. Pediatric Clinics of North America, 55, 89–1207.CrossRefGoogle Scholar
  9. Dougherty, N. J. (2009). A review of cerebral palsy for the oral health professional. Dental Clinics of North America, 53, 329–338.CrossRefPubMedGoogle Scholar
  10. Evans, P. M., Evans, S. J. W., > Alberman, E. (1990). Cerebral palsy: Why we must plan for survival. Archives of Disease in Childhood, 65, 1329–1333.CrossRefPubMedPubMedCentralGoogle Scholar
  11. Ferriero, D. H. (1999). Cerebral palsy: Diagnosing something that is not one thing. Current Opinion in Pediatrics, 11, 485–486.CrossRefPubMedGoogle Scholar
  12. Finckh, U., Schroder, J., Ressler, B., et al. (2000). Spectrum and detection rate of L1CAM mutations in isolated and familial cases with clinically suspected L1-disease. American Journal of Medical Genetics, 92, 40–46.CrossRefPubMedGoogle Scholar
  13. Fisher, R. L., > Russman, B. S. (1974). Genetic syndromes associated with cerebral palsy. Clinical Orthopaedics and Related Research, 99, 2–11.CrossRefPubMedGoogle Scholar
  14. Fryer, A., Appleton, R., Sweeney, M. G., et al. (1994). Mitochondrial DNA 8993 (NARP) mutation presenting with a heterogeneous phenotype including cerebral palsy. Archives of Disease in Childhood, 71, 419–422.CrossRefPubMedPubMedCentralGoogle Scholar
  15. Garne, E., Dolk, H., Krägeloh-Mann, I., et al. (2008). Cerebral palsy and congenital malformations. European Journal of Paediatric Neurology, 12, 82–88.CrossRefPubMedGoogle Scholar
  16. Green, L., Greenberg, G. M., > Hurwitz, E. (2003). Primary care of children with cerebral palsy. Clinics in Family Practice, 5, 467–491.CrossRefGoogle Scholar
  17. Guerrini, R., Moro, F., Kato, M., et al. (2007). Expansion of the first PolyA tract of ARX causes infantile spasms and status dystonicus. Neurology, 69, 427–433.CrossRefPubMedGoogle Scholar
  18. Kavčič, A., > Vodušek, D. B. (2005). A historical perspective on cerebral palsy as a concept and a diagnosis. European Journal of Neurology, 12, 582–587.CrossRefPubMedGoogle Scholar
  19. Krägeloh-Mann, I., > Cans, C. (2009). Cerebral palsy update (Review). Brain and Development, 31, 537–544.CrossRefPubMedGoogle Scholar
  20. Kuban, K. C. K., > Leviton, A. (1994). Cerebral palsy. The New England Journal of Medicine, 330, 188–195.CrossRefPubMedGoogle Scholar
  21. Liptak, G. S. (2005). Complementary and alternative therapies for cerebral palsies. Mental Retardation and Developmental Disabilities Research Reviews, 11, 156–163.CrossRefPubMedGoogle Scholar
  22. Paneth, N. (1986). Etiologic factors in cerebral palsy. Pediatric Annals, 15, 191–201.CrossRefPubMedGoogle Scholar
  23. Paneth, N. (2008). Establishing the diagnosis of cerebral palsy. Clinical Obstetrics and Gynecology, 51, 742–748.CrossRefPubMedGoogle Scholar
  24. Panteliadis, C. P. (2004). Classification. In C. P. Panteliadis > H. M. Strassburg (Eds.), Cerebral palsy: Principles and management. Stuttgart: Thieme.Google Scholar
  25. Poulton, J., > Turnbull, D. M. (2000). 74th ENMC international workshop: Mitochondrial diseases 19–20 November 1999, Naarden, the Netherlands. Neuromuscular Disorders, 10, 460–462.CrossRefPubMedGoogle Scholar
  26. Rogers, B. (2004). Feeding method and health outcomes of children with cerebral palsy. Journal of Pediatrics, 145, S28–S32.CrossRefPubMedGoogle Scholar
  27. Russman, B. S., > Ashwal, S. (2004). Evaluation of the child with cerebral palsy. Seminars in Pediatric Neurology, 11, 47–57.CrossRefPubMedGoogle Scholar
  28. Sanger, T. D., Delgado, M. R., Gaebler-Spira, D., et al. (2003). Classification and definition of disorders causing hypertonia in childhood. Pediatrics, 111, e89–e97.CrossRefPubMedGoogle Scholar
  29. Schaefer, G. B. (2008). Genetic s considerations in cerebral palsy. Seminars in Pediatric Neurology, 15, 21–26.CrossRefPubMedGoogle Scholar
  30. Shevell, M. I., Majnemer, A., > Morin, I. (2003). Etiologic yield of cerebral palsy: A contemporary case series. Pediatric Neurology, 28, 352–359.CrossRefPubMedGoogle Scholar
  31. Shimony, J. S., Lawrence, R., Neil, J. J., et al. (2008). Imaging for diagnosis and treatment of cerebral palsy. Clinical Obstetrics and Gynecology, 51, 787–799.CrossRefPubMedGoogle Scholar

Copyright information

© Springer Science+Business Media New York 2016

Authors and Affiliations

  1. 1.Medical GeneticsShriners Hospitals for ChildrenShreveportUSA
  2. 2.Perinatal and Clinical Genetics, Department of PediatricsLSU Health Sciences CenterShreveportUSA

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