Abstract
Vasculitis, inflammation of the vessel wall, can result in mural destruction with hemorrhage, aneurysm formation, and infarction, or intimal-medial hyperplasia and subsequent stenosis leading to tissue ischemia and infarction. The skin, in part due to its large vascular bed, exposure to cold temperatures, and frequent presence of stasis, is involved in many distinct as well as unnamed vasculitic syndromes that vary from localized and self-limited to generalized and life-threatening with multi-organ disease. Cutaneous vasculitis comprises a wide spectrum of overlapping primary and secondary disease entities that are characterized by predominant skin involvement and varying degrees of systemic manifestations (Carlson et al. 2005).
This is a preview of subscription content, log in via an institution.
References
Booth, A., Harper, L., Hammad, T., et al. (2004). Prospective study of TNFalpha blockade with infliximab in anti-neutrophil cytoplasmic antibody associated systemic vasculitis. Journal of the American Society of Nephrology, 15, 717–721.
Carlson, J. A., & Chen, K.-R. (2007). Cutaneous vasculitis update: Neutrophilic muscular vessel and eosinophilic, granulomatous, and lymphocytic vasculitis syndrome. The American Journal of Dermatopathology, 29, 32–43.
Carlson, J. A., Ng, B. T., & Chen, K.-R. (2005). Cutaneous vasculitis update: Diagnostic criteria, classification, epidemiology, etiology, pathogenesis, evaluation and prognosis. The American Journal of Dermatopathology, 27, 504–528.
Chen, K.-R., & Carlson, J. A. (2008). Clinical approach to cutaneous vasculitis. American Journal of Clinical Dermatology, 9(2), 71–92.
Garcia-Porrua, C., Llorca, J., Gonzalez-Louzao, C., et al. (2001). Hypersensitivity vasculitis in adults: A benign disease usually limited to skin. Clinical and Experimental Rheumatology, 19, 85–88.
Guillevin, L., Lhote, F., Amouroux, J., et al. (1996). Antineutrophil cytoplasmic antibodies, abnormal angiograms and pathological findings in polyarteritis nodosa and Churg-Strauss syndrome: Indications for the classification of vasculitides of the polyarteritis Nodosa Group. British Journal of Reumatology, 35, 958–964.
Jennette, J. C., Falk, R. J., Andrassy, K., et al. (1994). Nomenclature of systemic vasculitides. Proposal of an international consensus conference. Arthritis and Rheumatology, 37, 187–192.
Jennette, J. C., Falk, R. J., Bacon, P. A., et al. (2013). 2012 revised international Chapel Hill consensus conference nomenclature of vasculitides. Arthritis and Rheumatism, 65, 1–11.
Lotti, T., Ghersetich, I., Comacchi, C., et al. (1998). Cutaneous small-vessel vasculitis. Journal of the American Academy of Dermatology, 39, 667–687. quiz 688–90.
Raza, K., Thambyrajah, J., Townend, J. N., et al. (2000). Suppression of inflammation in primary systemic vasculitis restores vascular endothelial function: Lessons for atherosclerotic disease? Circulation, 102, 1470–1472.
Sais, G., Vidaller, A., Jucgla, A., et al. (1998). Prognostic factors in leukocytoclastic vasculitis: A clinicopathologic study of 160 patients. Archives of Dermatology, 134, 309–315.
Sorensen, S. F., Slot, O., Tvede, N., et al. (2000). A prospective study of vasculitis patients collected in a five year period: Evaluation of the Chapel Hill nomenclature. Annals of the Rheumatic Diseases, 59, 478–482.
Willcocks, L., Chelliah, G., Brown, R., et al. (2003). Cutaneous vasculitis – A case for laparotomy? Journal of Rheumatology, 30, 1621–1623.
Author information
Authors and Affiliations
Corresponding author
Rights and permissions
Copyright information
© 2015 Springer Science+Business Media New York
About this entry
Cite this entry
Chen, H. (2015). Cutaneous Vasculitis. In: Atlas of Genetic Diagnosis and Counseling. Springer, New York, NY. https://doi.org/10.1007/978-1-4614-6430-3_256-1
Download citation
DOI: https://doi.org/10.1007/978-1-4614-6430-3_256-1
Received:
Accepted:
Published:
Publisher Name: Springer, New York, NY
Online ISBN: 978-1-4614-6430-3
eBook Packages: Springer Reference Biomedicine and Life SciencesReference Module Biomedical and Life Sciences