Metagenome: The collective genomes of all members of a bacterial community.
Mobile metagenome: The total pool of mobile genetic elements associated with a bacterial community.
Mobile genetic element (MGE): A discrete genetic unit capable of mediating its own transfer between distinct DNA molecules, and/or between distinct host cells of the same or different species. Plasmids, transposons, insertion sequences, conjugative transposons, integrons, and bacteriophage are all examples of MGE.
Horizontal gene transfer: Transfer and acquisition of genetic material between distinct cells or species, outside of and in addition to the normal process of inheritance (vertical gene transfer).
The adult human gastrointestinal tract (GIT) is home to a dense population of microorganisms, reaching an estimated 1013–1014individual prokaryotic cells in the distal colon and dominated by bacteria from ~150 to...
KeywordsFermentation Carbohydrate Europe Polysaccharide Microbe
- McNiel NI. The contribution of the large intestine to energy supplies in man. Am J Clin Nutr. 1984;39:338–42.Google Scholar
- Smalla K, Osburne AM, Wellington EMH. Isolation and characterisation of plasmids from bacteria. In: CM Thomas (ed) The horizontal gene pool, bacterial plasmids and gene spread. Amsterdam: Harwood Academic Publishers; 2000. p. 207–48.Google Scholar