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Mining Metagenomic Datasets for Antibiotic Resistance Genes

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Encyclopedia of Metagenomics

Synonyms

Anthropogenic and human associated; Horizontal gene transfer and lateral gene transfer; Whole-genome sequencing and metagenomic sequencing

Definition

Metagenomics refers to samples in which the entire bacterial or microbial community DNA is used and to high-throughput DNA sequencing of microbial community DNA. These sample types and methods can be used to gather information on genes that code for antibiotic resistance.

Introduction

Antibiotics are medicines that are used to kill, slow down, or prevent the growth of susceptible bacteria. They became widely used in the mid-twentieth century for controlling disease in humans, animals, and plants and for a variety of industrial purposes. Antibiotic resistance is a broad term. Depending on the classification scheme used, there are between eight and twenty different classes of antibiotics, with multiple compounds in each class. These different categories represent different basic chemical structures and modes of action – some...

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Author information

Authors and Affiliations

  1. Agroecosystem Management Research Unit, US Department of Agriculture, University Of Nebraska, Lincoln- East Campus, Room 121 Keim Hall, Lincoln, NE, 68583-0938, USA

    Lisa Durso

Authors
  1. Lisa Durso
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Corresponding author

Correspondence to Lisa Durso .

Editor information

Editors and Affiliations

  1. J. Craig Venter Institute (JCVI), Rockville, Maryland, USA

    Karen E. Nelson

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© 2013 Springer Science+Business Media New York

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Durso, L. (2013). Mining Metagenomic Datasets for Antibiotic Resistance Genes. In: Nelson, K. (eds) Encyclopedia of Metagenomics. Springer, New York, NY. https://doi.org/10.1007/978-1-4614-6418-1_729-1

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  • DOI: https://doi.org/10.1007/978-1-4614-6418-1_729-1

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  • Publisher Name: Springer, New York, NY

  • Online ISBN: 978-1-4614-6418-1

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