The human oral cavity is a rich biological site with several microbial niches including teeth, gingival sulcus, tongue, cheek, hard and soft palates, tonsils, throat, and saliva. The microbiome of the oral cavity (Dewhirst et al. 2010) and its niches have been examined based on 16S rRNA sequencing (Aas et al. 2005; Bik et al. 2010; Human Microbiome Project 2012). The metagenome of the oral cavity has been studied to a limited degree prior to 2012 due to the complexity of the site (Alcaraz et al. 2012; Belda-Ferre et al. 2012; Xie et al. 2010). More than 700 prevalent species comprise the oral microbiome, but many taxa are present at less than 0.1 % of the microbial population (Dewhirst et al. 2010). As oral bacterial reference genomes are becoming available, primarily through the efforts of the Human Microbiome Project (Human Microbiome Project 2012), it is becoming possible to attribute metagenomic sequences to organisms at genus and species level (Martin et al. 2012)....
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Chen, T., Dewhirst, F. (2013). Human Oral Microbiome Database (HOMD). In: Nelson, K. (eds) Encyclopedia of Metagenomics. Springer, New York, NY. https://doi.org/10.1007/978-1-4614-6418-1_13-5
Publisher Name: Springer, New York, NY
Online ISBN: 978-1-4614-6418-1
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