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Next-Generation DNA Sequencing: Ion Torrent Sequencers Versus Nanopore Technology

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Handbook of Biochips

Abstract

Next-sequencing technology is evolving rapidly, and during the last 10 years, several new sequencing platforms were released. In particular, Ion Torrent and Oxford Nanopore have revolutionized almost every corner of the biomedical sciences. These two platforms are gaining popularity in the marketplace, mainly due to the use of native oligonucleotides, low cost of sequencing runs, and the possibility of their daily use without any technical requirements or maintenance. Since they arrived in the marketplace, we have witnessed tremendous technical improvement in these two technologies accompanied by active competition between them. This chapter aims to summarize, compare, and analyze these two technologies that have been developed recently towards short-/long-read sequencing and comprehensively highlight recent advances in improving the performance of these two technologies.

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Correspondence to Chaker Tlili or Deqiang Wang .

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© 2022 Springer Science+Business Media, LLC, part of Springer Nature

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Tlili, C. et al. (2022). Next-Generation DNA Sequencing: Ion Torrent Sequencers Versus Nanopore Technology. In: Sawan, M. (eds) Handbook of Biochips. Springer, New York, NY. https://doi.org/10.1007/978-1-4614-3447-4_56

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