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Copper, Mononuclear Monooxygenases

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Encyclopedia of Metalloproteins

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References

  • Blain I, Slama P, Giorgi M, Tron T, Réglier M (2002) Copper-containing monooxygenases: enzymatic and biomimetic studies of the oxygen atom transfer catalysis. Rev Mol Biotechnol 90:95–112

    Article  CAS  Google Scholar 

  • Bousquet-Moore D, Prohaska JR, Nillni EA, Czyzyk T, Wetsel WC, Mains RE, Eipper BA (2010) Interactions of peptide amidation and copper: novel biomarkers and mechanisms of neural dysfunction. Neurobiol Dis 37:130–140

    Article  CAS  PubMed  Google Scholar 

  • Chufán EE, Prigge ST, Siebert X, Eipper BA, Mains RE, Amzel LM (2010) Differential reactivity between two copper sites in peptidylglycine α-hydroxylating monooxygenase. J Am Chem Soc 132:15565–15572

    Article  PubMed  CAS  Google Scholar 

  • Evans JP, Ahn K, Klinman JP (2003) Evidence that dioxygen and substrate activation are tightly coupled in dopamine β-monooxygenase: implications for the reactive oxygen species. J Biol Chem 278:49691–49698

    Article  CAS  PubMed  Google Scholar 

  • Hess CR, McGuirl MM, Klinman JP (2008) Mechanism of the insect enzyme, tyramine β-monooxygenase, reveals differences from the mammalian enzyme, dopamine β-monooxygenase. J Biol Chem 283:3042–3049

    Article  CAS  PubMed  Google Scholar 

  • Hess CR, Klinman JP, Blackburn NJ (2010) The copper centers of tyramine β-monooxygenase and its catalytic-site methionine variants: an X-ray absorption study. J Biol Inorg Chem 15:1195–1207

    Article  CAS  PubMed  Google Scholar 

  • Klinman JP (1996) Mechanisms whereby mononuclear copper proteins functionalize organic substrates. Chem Rev 96:2541–2561

    Article  CAS  PubMed  Google Scholar 

  • Kulathila R, Merkler KA, Merkler DJ (1999) Enzymatic formation of C-terminal amides. Nat Prod Rep 16:145–154

    Article  CAS  PubMed  Google Scholar 

  • Prigge ST, Kolhekar AS, Eipper BA, Mains RE, Amzel LM (1997) Amidation of bioactive peptides: the structure of peptidylglycine hydroxylating monooxygenase. Science 278:1300–1305

    Article  CAS  PubMed  Google Scholar 

  • Prigge ST, Kolhekar AS, Eipper BA, Mains RE, Amzel LM (1999) Substrate-mediated electron transfer in peptidylglycine α-hydroxylating monooxygenase. Nat Struct Biol 6:976–983

    Article  CAS  PubMed  Google Scholar 

  • Prigge ST, Eipper BA, Mains RE, Amzel LM (2004) Dioxygen binds end-on to mononuclear copper in a precatalytic enzyme complex. Science 304:864–867

    Article  CAS  PubMed  Google Scholar 

  • Senard JM, Rouet P (2006) Dopamine β-hydroxylase deficiency. Orphanet J Rare Dis 1:1–4

    Article  Google Scholar 

  • Stewart LC, Klinman JP (1988) Dopamine β-hydroxylase of adrenal chromaffin granules: structure and function. Annu Rev Biochem 57:551–592

    Article  CAS  PubMed  Google Scholar 

  • Xin X, Mains RE, Eipper BA (2004) Monooxygenase X a member of the copper-dependent monooxygenase family localized to the endoplasmic reticulum. J Biol Chem 279:48159–48167

    Article  CAS  PubMed  Google Scholar 

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Correspondence to Marius Réglier Ph.D. .

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Réglier, M., Belle, C. (2013). Copper, Mononuclear Monooxygenases. In: Kretsinger, R.H., Uversky, V.N., Permyakov, E.A. (eds) Encyclopedia of Metalloproteins. Springer, New York, NY. https://doi.org/10.1007/978-1-4614-1533-6_97

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