Encyclopedia of Metalloproteins

2013 Edition
| Editors: Robert H. Kretsinger, Vladimir N. Uversky, Eugene A. Permyakov

Cobalt Transporters

  • Thomas Eitinger
Reference work entry
DOI: https://doi.org/10.1007/978-1-4614-1533-6_74



Import systems that transport the transition metal ion across cell membranes in order to provide it for synthesis of coenzyme B12 and for incorporation into cobalt-containing enzymes.


Cobalt is a trace nutrient for prokaryotes and utilized for biosynthesis of the cobalt-containing coenzyme B12 (see also  Vitamin B12), and for incorporation into noncorrin  Co-containing enzymes. Animals must take up vitamin B12 with their diet or from intestinal prokaryotic producers. In higher plants, physiological roles for corrin and noncorrin cobalt enzymes have so far not been established. Nevertheless, beneficial effects of Co2+ for plant growth are known (Pilon-Smits et al. 2009). These effects may be due to stimulating growth of bacteria in the rhizosphere and of root-nodulating bacterial endosymbionts.

The focus of this short survey is on import systems in prokaryotes that transport Co 2+ions with high affinity and...
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Copyright information

© Springer Science+Business Media New York 2013

Authors and Affiliations

  1. 1.Institut für Biologie/Mikrobiologie, Humboldt-Universität zu BerlinBerlinGermany