Calcium Sparklets and Waves
A kinase anchoring protein 150 (AKAP150); Calcium concentration [Ca2+]; Calcium-induced calcium release (CICR); Calmodulin (CaM); Cyclic adenosine monophosphate (cAMP); Excitation-contraction coupling (EC coupling), excitation-transcription coupling (ET coupling); Förster resonance energy transfer (FRET); Inositol triphosphate (IP3); Inositol triphosphate receptors (IP3Rs); Myosin light chain (MLC); nuclear factor of activated T-cell c3 (NFATc3); Protein kinase A (PKA); Protein kinase Cα (PKCα); Protein phosphatase 2B or calcineurin (PP2B); Ryanodine receptors (RyRs); Sarcoplasmic reticulum (SR); Timothy syndrome (TS); Total internal reflection fluorescence (TIRF)
Ca2+ sparklets are local Ca2+ signals produced by the opening of dihydropyridine-sensitive, voltage-gated L-type Ca2+ channels in the plasma membrane of neurons and muscle.
Ca2+ waves are propagating cell-wide increases in cytosolic [Ca2+].
Ca2+ sparks are local Ca2+...
- Hille B (2001) Ionic channels of excitable membranes, 3rd edn. Sinauer Associates, SuderlandGoogle Scholar