Ca2+-regulated photoprotein is a “precharged” bioluminescent protein from which light emission is triggered by addition of calcium ions. The bioluminescence reaction does not require addition of molecular oxygen or any other cofactors, only the photoprotein and the triggering ion are necessary.
Bioluminescence is widespread in the biosphere. Luminous organisms have been found among bacteria, fungi, protozoa, coelenterates, worms, mollusks, insects, and fish. Although these organisms occupy different places in the evolutionary ladder, the nature of their bioluminescence is always the same. In fact, bioluminescence is a chemiluminescent reaction whereby oxidation of a substrate, luciferin, is catalyzed by a specific enzyme, luciferase. Luciferins and luciferases of different organisms differ in structure; that is, the terms are generic and functional rather than structural and chemical. The many differences suggest that...
- Vysotski ES, Lee J (2007) Bioluminescence mechanism of Ca2+-regulated photoproteins from three-dimensional structures. In: Viviani VR, Ohmiya Y (eds) Luciferases and fluorescent proteins: principles and advances in biotechnology and bioimaging. Transworld Research Network, KeralaGoogle Scholar