Silver, Burn Wound Sepsis and Healing
Topical treatment and burn wound dressings are an essential component of burn wound management. Several topical agents are being used to reduce surface colonization and prevent burn wound sepsis. Silver-based products have been most widely used over the last few decades and since the introduction of the silver-containing formulation, silver sulfadiazine (SSD) (Flamazine®, Silvadene®), by Fox shortly, silver became the main antibacterial prophylactic agent in burns and a viable treatment option for burn wounds, open wounds, and chronic ulcers. Nevertheless, the use of the many silver-containing products for burn wounds is still controversial and opinions in clinical practice conflicting.
Silver does possess antimicrobial properties. However, evidence of its effectiveness remains poorly defined and does not support its use for topical treatment. Silver does not appear to...
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