Definition
Silicon is extremely common in nature where it occurs as silicon dioxide and various silicates. The primary role of silicon-containing compounds in biological environment is a structural one with silicates incorporated into exoskeleton of marine organisms, cell walls of plants, and connective tissues of animals.
Introduction
Silicon is the second most abundant element in the Earth’s crust accounting for 27.7% of it by weight. Silicon is the closest analogue of carbon in periodic table. However, it is more electropositive, resulting in stronger Si-O bonds and much weaker Si-Si and Si-H bonds compared to carbon. High stability of Si-O bond makes formation of silicon dioxide and silicates highly thermodynamically favorable. Silica and most silicates are poorly water soluble and highly chemically stable. Due to their high stability, silicon dioxide and silicates are the only silicon-containing...
Access this chapter
Tax calculation will be finalised at checkout
Purchases are for personal use only
References
Carlisle EM (1984) Silicon. In: Frieden E (ed) Biochemistry of the essential ultratrace elements. Plenum Press, New York, pp 319–340
Kroger N, Lehmann G, Rachel R, Sumper M (1997) Characterization of a 200-kDa diatom protein that is specifically associated with a silica-based substructure of the cell wall. Eur J Biochem 250:99–105
Ma JF, Tamai K, Yamaji N, Mitani N, Konishi S, Katsuhara M, Ishiguro M, Murata Y, Yano M (2006) A silicon transporter in rice. Nature 440:688–691
Ma JF, Yamaji N, Mitani N, Tamai K, Konishi S, Fujiwara T, Katsuhara M, Yano M (2007) An efflux transporter of silicon in rice. Nature 448:209–212
Poulsen N, Sumper M, Kroger N (2003) Biosilica formation in diatoms: characterization of native silaffin-2 and its role in silica morphogenesis. Proc Natl Acad Sci USA 100:12075–12080
Rezanka T, Sigler K (2008) Biologically active compounds of semi-metals. Phytochemistry 69:585–606
Sumper M, Lorenz S, Brunner E (2003) Biomimetic control of size in the polyamine-directed formation of silica nanospheres. Angew Chem Int Ed Engl 42:5192–5195
Wang X, Schlossmacher U, Wiens M, Batel R, Schroder HC, Muller WE (2012) Silicateins, silicatein interactors and cellular interplay in sponge skeletogenesis: formation of glass fiber-like spicules. FEBS J 279:1721–1736
Author information
Authors and Affiliations
Corresponding author
Editor information
Editors and Affiliations
Rights and permissions
Copyright information
© 2013 Springer Science+Business Media New York
About this entry
Cite this entry
Breydo, L. (2013). Silicon, Biologically Active Compounds. In: Kretsinger, R.H., Uversky, V.N., Permyakov, E.A. (eds) Encyclopedia of Metalloproteins. Springer, New York, NY. https://doi.org/10.1007/978-1-4614-1533-6_486
Download citation
DOI: https://doi.org/10.1007/978-1-4614-1533-6_486
Publisher Name: Springer, New York, NY
Print ISBN: 978-1-4614-1532-9
Online ISBN: 978-1-4614-1533-6
eBook Packages: Biomedical and Life SciencesReference Module Biomedical and Life Sciences