Selenium and Muscle Function
Cardiovascular disorders; Cardiomyopathy; Chagas disease; Exudative diathesis; Keshan disease; Mallory Body-like Desmin-Related Myopathy (MB-DRM); Multiminicore disease (MmD); Myopathy with Congenital Fiber Type Disproportion (CFTD); Myotonic dystrophies; Nutritional muscular dystrophy; Rigid lamb syndrome; Rigid Spine Muscular Dystrophy (RSMD1); Selenoprotein 15 kDa (Sep15); Selenoprotein K (SelK); Selenoprotein N (SelN, SepN); Selenoprotein S (SelS); Selenoprotein T (SelT); SEPN1 gene; SEPN1-related myopathies (SEPN1-RM); White muscle disease
Selenium deficiencies have been linked to different forms of cardiac and skeletal muscle diseases in human and livestock, and selenium supplementation has been proved to be protective against the emergence of these disorders. Selenium is incorporated as selenocysteine into several enzymes that play a critical role in oxidative-reduction homeostasis. Several of these enzymes are supposed to play important...
- Castets P, Lescure A, Guicheney P, Allamand V (2012) Selenoprotein N in skeletal muscle: from diseases to function. J Mol Med (Berl) [Epub ahead of print]Google Scholar