Encyclopedia of Metalloproteins

2013 Edition
| Editors: Robert H. Kretsinger, Vladimir N. Uversky, Eugene A. Permyakov

Cesium, Therapeutic Effects and Toxicity

  • Petr Melnikov
  • Lourdes Zélia Zanoni
Reference work entry
DOI: https://doi.org/10.1007/978-1-4614-1533-6_352



The aim of this entry is to resume and discuss the material currently available on therapeutic effects of cesium salts, their applications in medicine, and their toxicity.


Cesium is naturally present as the stable 133Cs in various ores and to a lesser extent in soil. The most important radioactive nuclides are 131Cs and 137Cs, with half-lives of 10 days and 30 years, respectively. Cesium enters easily into the plant and animal systems and is deposited in soft tissues. The total content of this intracellular form is very low, no more than 0.00131 g. Cesium salts are used as catalysts and for the production of special glasses and ceramics. In molecular biology, they are applied for decades for density gradient ultracentrifugation in order to isolate viral particles, subcellular organelles and fractions, and nucleic acids from biological samples.

An extensive...

This is a preview of subscription content, log in to check access.


  1. Gmelin’s L (1973) Handbuch der AnorganischenChemie (System Number 20), 8th edn. Springer, Berlin/Heidelberg/New YorkGoogle Scholar
  2. Melnikov P, Zanoni LZ (2010) Clinical effects of cesium intake. Biol Trace Elem Res 135(1–3):1–9CrossRefPubMedGoogle Scholar
  3. U.S. Department of Health and Human Services.Public Health Service (2004) Toxicological profile for cesium. Agency for Toxic Substances and Diseases Registry.Cesium- Health Effects, AtlantaGoogle Scholar

Copyright information

© Springer Science+Business Media New York 2013

Authors and Affiliations

  1. 1.Department of Clinical Surgery, School of MedicineFederal University of Mato Grosso do SulCampo GrandeBrazil
  2. 2.Department of Pediatrics, School of MedicineFederal University of Mato Grosso do SulCampo GrandeBrazil