Synonyms
Adaptation: Acclimatization; Refitting
Resistance: Insusceptibility; Obstruction; Opposition; Resistivity
Definition
Adaptation: The fact for a living species to become better suited to its environment.
Resistance: The process of opposing the harmful threat of a toxic compound.
Speciation: Describes the associated forms in which elements, e.g., metals, occur in complex systems, such as a biological medium.
Redox: Acronym for oxidation-reduction. Here, refers to the set of reactions in which electrons can be exchanged within a cell.
Reactive oxygen species (ROS): Designates three oxygen-containing compounds, the superoxide radical anion, hydrogen peroxide, and hydroxyl radical, which all derive from dioxygen by successive reduction steps. By extension, ROS may refer to strongly oxidative (i.e., electron withdrawing) oxygen-containing molecules such as the hypochlorous anion or peroxynitrite.
Introduction
Cadmium compounds are overwhelmingly toxic in their interactions with...
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References
Beyersmann D, Hechtenberg S (1997) Cadmium, gene regulation, and cellular signalling in mammalian cells. Toxicol Appl Pharmacol 144:247–261
Clemens S (2006) Toxic metal accumulation, responses to exposure and mechanisms of tolerance in plants. Biochimie 88:1707–1719
Cuypers A, Plusquin M, Remans T, Jozefczak M, Keunen E, Gielen H, Opdenakker K, Nair AR, Munters E, Artois TJ, Nawrot T, Vangronsveld J, Smeets K (2010) Cadmium stress: an oxidative challenge. Biometals 23:927–940
Fauchon M, Lagniel G, Aude JC, Lombardia L, Soularue P, Petat C, Marguerie G, Sentenac A, Werner M, Labarre J (2002) Sulfur sparing in the yeast proteome in response to sulfur demand. Mol Cell 9:713–723
Hartwig A (2010) Mechanisms in cadmium-induced carcinogenicity: recent insights. Biometals 23:951–960
He L, Wang B, Hay EB, Nebert DW (2009) Discovery of ZIP transporters that participate in cadmium damage to testis and kidney. Toxicol Appl Pharmacol 238:250–257
Klaassen CD, Liu J, Diwan BA (2009) Metallothionein protection of cadmium toxicity. Toxicol Appl Pharmacol 238:215–220
Liu J, Qu W, Kadiiska MB (2009) Role of oxidative stress in cadmium toxicity and carcinogenesis. Toxicol Appl Pharmacol 238:209–214
Maret W (2011) Redox biochemistry of mammalian metallothioneins. J Biol Inorg Chem 16(7):1079–1086
Morel FM (2008) The co-evolution of phytoplankton and trace element cycles in the oceans. Geobiology 6:318–324
Moulis JM (2010) Cellular mechanisms of cadmium toxicity related to the homeostasis of essential metals. Biometals 23:877–896
Satarug S, Garrett SH, Sens MA, Sens DA (2010) Cadmium, environmental exposure, and health outcomes. Environ Health Perspect 118:182–190
Thévenod F (2009) Cadmium and cellular signaling cascades: to be or not to be? Toxicol Appl Pharmacol 238:221–239
Thévenod F (2010) Catch me if you can! Novel aspects of cadmium transport in mammalian cells. Biometals 23:857–875
Villiers F, Ducruix C, Hugouvieux V, Jarno N, Ezan E, Garin J, Junot C, Bourguignon J (2011) Investigating the plant response to cadmium exposure by proteomic and metabolomic approaches. Proteomics 11:1650–1663
Waalkes MP (2003) Cadmium carcinogenesis. Mutat Res 533:107–120
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Moulis, JM. (2013). Cadmium Exposure, Cellular and Molecular Adaptations. In: Kretsinger, R.H., Uversky, V.N., Permyakov, E.A. (eds) Encyclopedia of Metalloproteins. Springer, New York, NY. https://doi.org/10.1007/978-1-4614-1533-6_28
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DOI: https://doi.org/10.1007/978-1-4614-1533-6_28
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