Encyclopedia of Metalloproteins

2013 Edition
| Editors: Robert H. Kretsinger, Vladimir N. Uversky, Eugene A. Permyakov

Sodium/Potassium-ATPase Structure and Function, Overview

Reference work entry
DOI: https://doi.org/10.1007/978-1-4614-1533-6_243

Synonyms

Definition

The Na+,K+-ATPase is a transmembrane protein found in nearly all animal cells. It couples the energy released from the hydrolysis of the gamma phosphate of ATP to the transport of sodium and potassium ions across the cell membrane in a process called active transport. It is responsible, to a large extent, for the maintenance of transmembrane sodium and potassium concentration gradients and transmembrane electrical potential gradients. These gradients are in turn utilized by numerous biological processes, many of which are essential for higher-order life.

Historical Perspective

Most cells and particularly animal cells establish low...

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References

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Copyright information

© Springer Science+Business Media New York 2013

Authors and Affiliations

  1. 1.Department of Medicine and the Proteomics CenterStony Brook UniversityStony BrookUSA