Encyclopedia of Metalloproteins

2013 Edition
| Editors: Robert H. Kretsinger, Vladimir N. Uversky, Eugene A. Permyakov

Strontium Binding to Proteins

  • Vladimir N. Uversky
Reference work entry
DOI: https://doi.org/10.1007/978-1-4614-1533-6_175



Due to the general similarity between the strontium and calcium ions (both metals are members of the alkaline earth series (Group IIB of the Periodic Table) that have many common properties, such that both have two positive charges in their ionic forms, similar ionic radii, and the ability to form complexes of various binding strengths), strontium can replace calcium to some extent in various biochemical processes in the body, for example, being able to interact with many calcium-binding proteins. Being heavier than calcium, strontium is frequently used as a tracer for calcium. It is also an important and useful analog of calcium in clinical research. Strontium has been safely used as a medicinal substance for more than a 100 years.

Some Physicochemical Properties of Strontium

The chemical element strontium is the 38th element in the chemical periodic table with the symbol of Sr, atomic number of 38, and atomic mass of the...

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Copyright information

© Springer Science+Business Media New York 2013

Authors and Affiliations

  1. 1.Department of Molecular MedicineUniversity of South Florida, College of MedicineTampaUSA