Encyclopedia of Metalloproteins

2013 Edition
| Editors: Robert H. Kretsinger, Vladimir N. Uversky, Eugene A. Permyakov

Chromium and Allergic Reponses

  • Peter JensenEmail author
  • Jacob P. Thyssen
Reference work entry
DOI: https://doi.org/10.1007/978-1-4614-1533-6_13



Contact dermatitis: A skin reaction (dermatitis, i.e., eczema) resulting from exposure to allergens (allergic contact dermatitis) or irritants (irritant contact dermatitis).


Chromium (Cr) (Greek chroma, meaning color) is one of the most widely distributed metals and was discovered in 1797 by the French chemist Louis Nicolas Vauqelin who named it after its color characteristics. Cr is found in nature as Cr ironstone (FeCr2O4) and as red lead ore (PbCrO4, chrocoite). Cr ironstone is used commercially and is mined in southern parts of Africa, the Philippines, and Kazakhstan. The majority is used for metallurgical purposes such as stainless steel and other alloys. It is also used for leather tanning, preservation of woods, color pigments in paints, and laboratory chemicals. In addition, Cr compounds are present in raw materials used for the production of cement....

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Peter Jensen was supported by a grant from the Michaelsen Foundation.


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© Springer Science+Business Media New York 2013

Authors and Affiliations

  1. 1.Department of Dermato-AllergologyCopenhagen University Hospital GentofteHellerupDenmark
  2. 2.National Allergy Research Centre, Department of Dermato-AllergologyCopenhagen University Hospital GentofteHellerupDenmark