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Aluminum, Biological Effects

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Encyclopedia of Metalloproteins

Synonyms

Aluminum and health; Behavior of aluminum in biological systems

Definition

This entry refers to the ways of exposure of various biological systems to aluminum and to the mechanisms underlying the interactions of the element with these systems. Concerns on aluminum toxicity on ecosystems gain interest in view of the continuously increasing use of aluminum compounds in industry and acid rain.

Introduction

Despite the ubiquity of aluminum (Al) in the environment and its presence in living organisms, be it in small amounts (ppb-ppm range), no biological function has so far been attributed to the element. For this reason aluminum is considered a nonessential metal. It has long been thought that aluminum was inert for living organisms and as such was not regarded as a toxic element until the 1960s. At that time, only a few reports dealt with the toxic effects of aluminum in humans and animals, which, however, did not receive much attention. In the 1970s, aluminum exposure was linked...

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Correspondence to Patrick C. D’Haese .

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D’Haese, P.C. (2013). Aluminum, Biological Effects. In: Kretsinger, R.H., Uversky, V.N., Permyakov, E.A. (eds) Encyclopedia of Metalloproteins. Springer, New York, NY. https://doi.org/10.1007/978-1-4614-1533-6_110

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