Calcinosis Cutis

doi:10.1007/978-1-4614-1037-9_30

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Calcinosis cutis is a group of disorders characterized by the deposition of crystals of calcium phosphate (hydroxyapatite) in the skin in various areas of the body (Ianello et al. 1998) and can be associated with both normal and elevated calcium levels. Classically, it is divided into dystrophic, metastatic, iatrogenic, and idiopathic types.

Synonyms and Related Disorders

Calcinosis cutis (dystrophic, metastatic, iatrogenic, or idiopathic types)

Genetics/Basic Defects

1.
Dystrophic calcinosis cutis (Nunley and Jones 2009)
1. a.
  A common form of calcinosis cutis
2. b.
  Localized or generalized
3. c.
  Absence of calcium or phosphorus metabolic abnormalities
4. d.
  Depositions of calcium salts: secondary to local inflammation, tissue damage, and degeneration
5. e.
  Localized tissue damage
  1. i.
    Trauma
  2. ii.
    Burn
  3. iii.
    Inflammatory processes
    1. a)
      Acne
    2. b)
      Insect bites
  4. iv.
    Varicose veins
  5. v.
    Infections: Necrotic tissue produced by an infectious process may subsequently become calcified.

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References

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Editors and Affiliations

Perinatal and Clinical Genetics, Department of Pediatrics, LSU Health Sciences Center, 1501 Kings Highway, Shreveport, LA, 71130, USA
Harold Chen

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(2012). Calcinosis Cutis. In: Chen, H. (eds) Atlas of Genetic Diagnosis and Counseling. Springer, New York, NY. https://doi.org/10.1007/978-1-4614-1037-9_30

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DOI: https://doi.org/10.1007/978-1-4614-1037-9_30
Publisher Name: Springer, New York, NY
Print ISBN: 978-1-4614-1036-2
Online ISBN: 978-1-4614-1037-9
eBook Packages: Biomedical and Life SciencesReference Module Biomedical and Life Sciences

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