Dicentric chromosomes are among the most common structural changes of the Y chromosome (deletions, rings, Y-autosomal or Y–X translocations, isochromosomes, and dicentrics). Among these structural abnormalities, dicentric Y chromosomes are the most commonly found (Hsu 1994; Yoshida et al. 1997).
The dicentric Y chromosomes have two different types: dic(Yq), resulting from the fusion between the short arms of two Y chromosomes in which some Yp material is maintained, and dic(Yp) in which only the Yq arms fuse (Codina-Pascual et al. 2004). If the dicentric has completely symmetric arms, it is considered an isodicentric chromosome. The sites of breakage and fusion at Yp and Yq are variable (Robinson et al. 1999).
Synonyms and Related Disorders
Isodicentric chromosome Yq syndrome
KeywordsShort Stature Turner Syndrome Gonadal Dysgenesis Dicentric Chromosome Ambiguous Genitalia
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