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Idic(Yq) Syndrome

Reference work entry

Dicentric chromosomes are among the most common structural changes of the Y chromosome (deletions, rings, Y-autosomal or Y–X translocations, isochromosomes, and dicentrics). Among these structural abnormalities, dicentric Y chromosomes are the most commonly found (Hsu 1994; Yoshida et al. 1997).

The dicentric Y chromosomes have two different types: dic(Yq), resulting from the fusion between the short arms of two Y chromosomes in which some Yp material is maintained, and dic(Yp) in which only the Yq arms fuse (Codina-Pascual et al. 2004). If the dicentric has completely symmetric arms, it is considered an isodicentric chromosome. The sites of breakage and fusion at Yp and Yq are variable (Robinson et al. 1999).

Synonyms and Related Disorders

Isodicentric chromosome Yq syndrome

Genetics/Basic Defects

  1. 1.
    Isochromosome (DesGroseilliers et al. 2006)
    1. a.

      A chromosome with identical chromosome material in which two arms are mirror images and are of equal length.

       
    2. b.

      An isochromosome can be...

Keywords

Short Stature Turner Syndrome Gonadal Dysgenesis Dicentric Chromosome Ambiguous Genitalia 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

References

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