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Sinoacutine

Reference work entry

CAS Registry Number: 4090-18-0 (salutaridine) Open image in new window

Taxonomy: Physicochemical and Pharmacological Properties of Alkaloids – Isoquinoline Alkaloids

Biological sources: Stephania glabra, S. rotunda

C19H21NO4: 327.1471

Mp: 205–206°C [1], 180°C (hydrochloride), 226°C (picrate), 175°C (Ac)

[α]D −70° (CHCl3), [α]D −116° (EtOH) [2], [α]D −125° (EtOH)

UV: 242, 282(4.18, 3.60) [1]

IR: 3300, 1670 [1]

Pharm./Biol.: LD50 115 mg/kg (i/p, mice). Possesses weak ganglioblocking properties [3]

References

  1. 1.
    I.I. Shchelchkova, T.N. Il’inskaya, A.D. Kuzovkov, Chem. Nat. Comp. 1, 210 (1965)Google Scholar
  2. 2.
    J.C. Hsu, S.Y. Lo, J.H. Chu, Sci. Sinia 13, 2016 (1964). C. A., 62, 9183 (1965)Google Scholar
  3. 3.
    V.V. Berezhinskaya, S.S. Nikitina, S.A. Trutneva, Trudy VILR [Proceedings of the All-Union Scientific Research Institute of Drugs], Drugs [in Russian], 14, 58 (1971)Google Scholar

Copyright information

© Springer Science+Business Media New York 2013

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