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Narcotoline

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Natural Compounds
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CAS Registry Number: 521-40-4

Taxonomy: Physicochemical and Pharmacological Properties of Alkaloids – Isoquinoline Alkaloids

Biological sources: Papaver somniferum

C23H27NO8: 445.1737

Mp: 145–146°C [1]

UV: 220, 271, 288 sh [2]

IR(CHCl3): 3340, 1683, 1583, 1253, 1089, 1059, 995 [3]

1 H NMR: 2.25(6H, s, N(CH3)2), 3.86, 3.89, 3.97(each 3H, s, 3 × OCH3), 4.22(2H, s), 5.90(2H, s, CH2O2), 6.46(1H, s), 6.99, 7.84(each 1H, d, J = 8.5) [2]

HPLC: [4]

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References

  1. B. Proksa, J. Cerny, J. Putek, Pharmazie 34, 194 (1979)

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  2. R.H.F. Manske (ed.), The Alkaloids, Chemistry and Physiology, vol. 24 (Academic, New York, 1985), p. 253

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  3. G. Blasko, D.J. Gula, M. Shamma, J. Nat. Prod. 45, 105 (1982)

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  4. M. Johansson, D. Westerlund, J. Chromatogr. 452, 241 (1988)

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(2013). Narcotoline. In: Azimova, S.S., Yunusov, M.S. (eds) Natural Compounds. Springer, New York, NY. https://doi.org/10.1007/978-1-4614-0560-3_877

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