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Taxonomy: Physicochemical and Pharmacological Properties of Alkaloids – Isoquinoline Alkaloids

Biological sources: Corydalis caucasica, C. pseudoadunca, C. stricta

C21H21NO6: 383.1369

Mp: 131–132°C (MeOH) [1], 206°C (methiodide [MeOH])

[α]D+63° [1]

UV: 298 [2]

IR: 1760 [2]

MSm/z: 190 [2]

1H NMR: 2.57(3H, s, NCH3), 3.92, 4.08(each 3H, s, 2 × OCH3), 3.99, 5.49(each 1H, d, J = 4), 5.92(2H, s, CH2O2), 6.39, 6.58(each 1H, s, p–H–Ar), 6.52, 7.08(each 1H, d, J = 8, o–H–Ar) [3]

13 C NMR: [ 4]

Table 1

C-1

66.0

C-8

107.3

C-5′

147.5

3

49.0

8a

130.0

6′

119.4

4

26.7

9

82.7

10

167.0

4a

124.5

1′

140.4

NCH3

44.7

5

108.1

2′

117.3

6,7-OCH2O

100.5

6

146.3

3′

118.5

4′-OCH3

56.7

7

145.4

4′

152.6

5′-OCH3

62.0

References

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