CAS Registry Number: 49870-84-0
Taxonomy: Physicochemical and Pharmacological Properties of Alkaloids – Isoquinoline Alkaloids
Biological sources: Hypecoum erectum
C20H18N2O4: 350.1266
Mp: 235–239°C (dec., hydrochloride, MeOH) [1]
UV(hydrochloride): 245, 312, 380
IR(hydrochloride): 3420, 2440, 1580, 1570 [1]
MS m/z (hydrochloride): 350(H–HCl), 306(100) [1]
1 H NMR(hydrochloride, CF3COOH): 2.88(3H, m, J = 6), 2.70–3.80(4H, m), 6.10, 6.48(each 2H, s, 2 × CH2O2), 6.95, 6.97(each 1H, s, p–H–Ar), 7.78, 7.95(each 1H, d, J = 9, o–H–Ar), 8.18(1H, br s), 9.51(1H) [1]
Pharm./Biol.: Antimicrobial activity [2]
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G. Nonaka, I. Nishioka, Chem. Pharm. Bull. 21, 1410 (1973)
O.N. Tolkachev, L.D. Yakhontova, S.A. Vichkanova, T.V. Fateeva, in: Abstracts of Lectures at an All-Union Conference on the Results and Prospects of Scientific Investigations in the Field of Creating Drugs from Plant Raw Material [in Russian], Moscow, 1985, p. 56
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(2013). Corydamine. In: Azimova, S.S., Yunusov, M.S. (eds) Natural Compounds. Springer, New York, NY. https://doi.org/10.1007/978-1-4614-0560-3_831
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