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Corydamine

Reference work entry

CAS Registry Number: 49870-84-0 Open image in new window

Taxonomy: Physicochemical and Pharmacological Properties of Alkaloids – Isoquinoline Alkaloids

Biological sources: Hypecoum erectum

C20H18N2O4: 350.1266

Mp: 235–239°C (dec., hydrochloride, MeOH) [1]

UV(hydrochloride): 245, 312, 380

IR(hydrochloride): 3420, 2440, 1580, 1570 [1]

MSm/z (hydrochloride): 350(H–HCl), 306(100) [1]

1H NMR(hydrochloride, CF3COOH): 2.88(3H, m, J = 6), 2.70–3.80(4H, m), 6.10, 6.48(each 2H, s, 2 × CH2O2), 6.95, 6.97(each 1H, s, p–H–Ar), 7.78, 7.95(each 1H, d, J = 9, o–H–Ar), 8.18(1H, br s), 9.51(1H) [1]

Pharm./Biol.: Antimicrobial activity [2]

References

  1. 1.
    G. Nonaka, I. Nishioka, Chem. Pharm. Bull. 21, 1410 (1973)Google Scholar
  2. 2.
    O.N. Tolkachev, L.D. Yakhontova, S.A. Vichkanova, T.V. Fateeva, in: Abstracts of Lectures at an All-Union Conference on the Results and Prospects of Scientific Investigations in the Field of Creating Drugs from Plant Raw Material [in Russian], Moscow, 1985, p. 56Google Scholar

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© Springer Science+Business Media New York 2013

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