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Coclafine

Reference work entry

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Taxonomy: Physicochemical and Pharmacological Properties of Alkaloids – Isoquinoline Alkaloids

Biological source: Cocculus laurifolius

C16H19NO2: 257.1416

Mp: 264–266°C (Me2CO) [1]

[α]D +255° (MeOH) [1]

Solubility: spar. sol. Et2O, C6H6; very sol. EtOH [1]

UV: 208, 230, 285(4.30, 3.71, 3.41) [1]

IR: 3455, 1585, 1510 [1]

MSm/z: 257(M+), 240, 213, 212, 196, 150 [1]

1H NMR(CD3OD): 5.58(1H, br s, W1/2 = 7), 6.54(1H, br s), 6.58(1H, dd, J = 8; 3), 6.92(1H, d, J = 8) [1]

Abs. conf.: 3S, 5R [1]

References

  1. 1.
    R. Ziyaev, A. Abdusamatov, M.S. Yunusov, S.Yu. Yunusov, Chem. Nat. Comp. 27, 73 (1991)Google Scholar

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© Springer Science+Business Media New York 2013

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