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Cocculidine

Reference work entry

CAS Registry Number: 27675-40-7 Open image in new window

Taxonomy: Physicochemical and Pharmacological Properties of Alkaloids – Isoquinoline Alkaloids

Biological sources: Cocculus laurifolius

C18H23NO2: 285.1729

Mp: 86–87°C (pet. ether), 175°C (hydroiodide), 138°C (nitrate), 239°C (methiodide) [1]

[α]D +251° (CHCl3)

MSm/z: 285(M+), 270, 254, 227(100), 220, 196 [2]

Pharm./Biol.: LD50 93, 7.3 mg/kg (s/c, i/v, mice). Pronounced influence on conditioned reflex activity [3]

References

  1. 1.
    S.Yu. Yunusov, Zh. Obshch. Khim. 20, 368 (1950)Google Scholar
  2. 2.
    S.Yu. Yunusov, R. Razzakov, Chem. Nat. Comp. 6, 69 (1970)Google Scholar
  3. 3.
    U.B. Zakirov, I.K. Kamilov, The Pharmacology of Alkaloids and Glycosides [in Russian] (Fan, Tashkent, 1967), p. 190Google Scholar

Copyright information

© Springer Science+Business Media New York 2013

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