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(−) –Bicuculline

Reference work entry

CAS Registry Number: 19730-80-4 Open image in new window

Biological sources: Corydalis ledebouriana, C. sewerzowii, Fumaria schleicheri

C20H17NO6: 367.1056

Mp: 193–195°C (MeOH–Me2CO) [1]

[α]D −110° (CHCl3) [1]

Abs. conf.: 1R, 9S [2]

Pharm./Biol.: Has low activity. In contrast to (+)-bicuculline, is not a blocker of GABA receptors [3]

References

  1. 1.
    M.S. Yunusov, S.Yu. Yunusov, Chem. Nat. Comp. 4, 54 (1968)Google Scholar
  2. 2.
    G.P. Moiseeva, I.A. Israilov, M.S. Yunusov, S.Yu. Yunusov, Chem. Nat. Comp. 14, 82 (1978)Google Scholar
  3. 3.
    A.E. Valeev, N.I. Chernyavskhaya, F.N. Dzhakhangirov, M.S. Yunusov, I.A. Israilov, Neirofiziologiya (6), 820 (1988)Google Scholar

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© Springer Science+Business Media New York 2013

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