Advertisement

Yatrorhizine

Reference work entry

Open image in new window

Taxonomy: Physicochemical and Pharmacological Properties of Alkaloids – Diisoquinoline Alkaloids

Biological sources: Berberis amurensis, B. crataegina, B. heteropoda, B. iliensis, B. integerrima, B. nummularia, B. oblonga, B. vulgaris, Mahonia aquifolia, Thalictrum minus

C20H20N+O4: 338.1392

Mp: 206°C (chloride), 210°C (iodide), 210°C (picrate), 225°C (nitrate) [1]

UV: 266, 347, 440(4.4, 4.4, 3.7) [2]

UV(OH): 245, 385 [3]

1H NMR(CD3OD): 3.94(3H, s, 2-OCH3), 4.07(3H, s, 10-OCH3), 4.17(3H, s, 9-OCH3), 6.65(1H, s, H-4), 7.45(1H, s, H-1), 7.88(1H, d, H-12), 8.02(1H, d, H-11), 8.56(1H, s, H-13), 9.58(1H, s, H-8) [3]

13 C NMR: [ 4]

Table 1

C-1

110.9

C-6

57.6

C-12a

128.2

2

149.4

8

145.2

13

119.3

3

146.5

8a

119.2

13a

134.9

4

116.3

9

151.5

13b

120.9

4a

130.2

10

145.2

2-OCH3

58.3

5

29.1

11

122.9

9-OCH3

63.0

   

12

125.7

10-OCH3

57.0

References

  1. 1.
    S.Yu. Yunusov, Alkaloidy (Fan, Tashkent, 1981), p. 135Google Scholar
  2. 2.
    M. Shamma, J.C.D. Hillman, Chem. Rev. 779 (1969)Google Scholar
  3. 3.
    J. Siwan, R. Verpoorte, G.F.A. van Essen, A. Baerheim Svendsen, Planta Med. 38, 24 (1980)Google Scholar
  4. 4.
    R.A. Hussain, J. Kim, C.W.W. Beecher, A.D. Kinghorn, Heterocycles 29, 2257 (1989)Google Scholar
  5. 5.
    S. Tosa, S. Ishihara, Y. Nose, T. Usikawa, S. Yoshida, H. Makazawa, T. Tomimatsu, Zasshi Shoyakugaku 43, 28 (1989). C. A., 111, 160355 (1989)Google Scholar
  6. 6.
    Z.P. Naidovich, E.A. Trutneva, O.N. Tolkachev, V.D. Vasil’eva, Farmatsiya 25(4), 33 (1976)Google Scholar

Copyright information

© Springer Science+Business Media New York 2013

Personalised recommendations