Corydaline

Reference work entry

CAS Registry Number: 518-69-4 Open image in new window

Taxonomy: Physicochemical and Pharmacological Properties of Alkaloids – Diisoquinoline Alkaloids

Biological sources: Corydalis glaucescens, C. ledebouriana, C. marschalliana, C. popovii

C22H27NO4: 369.1940

Mp: 134–135°C (MeOH) [1]

[α]D +300° (CHCl3) [1]

UV: 227, 282 [2]

IR: 3010, 2980, 2950, 2900, 2850, 2800, 1665, 1648, 1623, 1509, 1488, 1468, 1421, 1398, 1368, 1337, 1319, 1295, 1281, 1258, 1241, 1159, 1130, 1086, 1078, 1047, 1016, 973, 962, 942, 921, 873, 858, 838, 825, 814 [3]

MSm/z: 369(M+), 192, 190, 178(100) [4]

1H NMR: 0.98(3H, d, J = 7), 3.83(3H, s, OCH3), 3.89(9H, s, 3 × OCH3), 6.61, 6.84(each 1H, s, 2 × H–Ar), 6.72(2H, s, H–Ar) [4, 5]

13 C NMR: [ 5]

Table 1

C-1

109.0

C-8

54.5

C-13

38.4

2

147.3

8a

128.6

14

63.1

3

147.8

9

150.2

14a

128.6

4

111.3

 10

145.1

15

18.4

4a

128.5

 11

111.7

2-OCH3

55.8

5

29.4

 12

124.1

3-OCH3

55.9

6

51.5

12a

135.1

9-OCH3

60.1

       

10-OCH3

56.2

References

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  3. 3.
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