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Coptisine

Reference work entry

CAS Registry Number: 3486-66-6 Open image in new window

Taxonomy: Physicochemical and Pharmacological Properties of Alkaloids – Diisoquinoline Alkaloids

Biological sources: Dicranostigma lactucoides, D. franschetianum, Hypecoum erectum, Macleaya cordata

C19H14N+O4: 320.0923

Mp: 280°C (iodide), 219°C (EtOH, tetrahydro) [1]

UV(chloride): 229, 241, 268, 354, 363, 467 [2]

IR(chloride): 3630, 3450, 3010, 2940, 2880, 2860, 2750, 1469, 1460, 1450, 1358, 1317, 1268, 1161, 1138, 1116, 1094, 1003, 968, 920, 894, 854 [3]

1H NMR(CF3COOH): 6.10, 6.44(each 2H, s, 2 × CH2O2), 6.91, 7.46, 8.44, 9.41(each 1H, s, 4 × H–Ar), 7.81(2H, s, 2 × H–Ar) [4]

HPLC: [5]

References

  1. 1.
    L. Kuhn, S. Pfeifer, Pharmazie 18, 819 (1963)Google Scholar
  2. 2.
    S. Pavelka, E. Smekal, Collect. Czech. Chem. Commun. 41, 3157 (1976)Google Scholar
  3. 3.
    J. Holubek, O. Strouf, Spectral Data and Physical Constants of Alkaloids, vol. 1 (Prague Publishing House, Czechoslovak Academy of Sciences/Heyden & Son, London, 1965), No. 66Google Scholar
  4. 4.
    K. Jewers, A.H. Manchanda, P.N. Jenkins, J. Chem. Soc. Perkin Trans. II 1393 (1972)Google Scholar
  5. 5.
    N. Chang-Qun, L.-Y. He, J. Chromatogr. 542, 193 (1991)Google Scholar

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© Springer Science+Business Media New York 2013

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